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Patients should reach out if they experience persistent nausea, vomiting, or diarrhea that prevents adequate nutrition or hydration (which may lead to dehydration and kidney problems)

For patients with diabetes, the risk of diabetic retinopathy complications and hypoglycemia (when used with insulin or sulfonylureas) should be discussed with healthcare providers

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Most patients naturally avoid problematic foods after one or two bad experiences, as the medication creates a built-in consequence system